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Commit 2134d171 authored by Giovanna Ambrosini's avatar Giovanna Ambrosini
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Change the main README.txt file

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......@@ -19,7 +19,7 @@ make clean
make cleanbin
External packages
External software
============================================================================
For Bowtie, refer to the following link:
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......@@ -31,9 +31,9 @@ with a PWM:
using a fast string-matching algorithm (e.g bowtie).
2) use a conventional algorithm that scans DNA sequences with a PWM (matrix_scan).
matrix_scan first rescales the scoring matrix so as to have the maximum score
set to zero. It then computes the PWM score for each position along the sequence,
and drops out as soon as the score is below a re-computed cut-off value.
matrix_scan first rescales the scoring matrix so that the maximum score at each
position is set to zero. For each position along the sequence, it computes the sum
of weights and drops out as soon as the score is below the cut-off value.
The Web interface automatically chooses the most suitable method.
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